Jonathan Ponciano, The Motley Fool
Sat, March 21, 2026 astatine 5:18 PM CDT 4 min read
Kynam Capital Management disclosed successful a February 17, 2026, Securities and Exchange Commission (SEC) filing that it sold 469,041 shares of Syndax Pharmaceuticals (NASDAQ:SNDX), an estimated $8.18 cardinal commercialized based connected quarterly mean pricing.
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Kynam Capital Management’s Syndax presumption was reduced, present accounting for 10.81% of reportable 13F assets nether absorption pursuing the sale.
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Top holdings aft the filing:
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NASDAQ:COGT: $218.99 cardinal (14.3% of AUM)
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NASDAQ:VERA: $173.85 cardinal (11.3% of AUM)
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NASDAQ:SNDX: $169.15 cardinal (11.0% of AUM)
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NASDAQ:CLDX: $161.42 cardinal (10.5% of AUM)
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NASDAQ:PCVX: $134.84 cardinal (8.8% of AUM)
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As of Friday, shares of Syndax Pharmaceuticals were priced astatine $24.23, up 72% implicit the past twelvemonth and good outperforming the S&P 500’s astir 15% summation successful the aforesaid period.
| Price (as of Friday) | $24.23 |
| Market capitalization | $2.1 billion |
| Revenue (TTM) | $172.4 million |
| Net income (TTM) | ($285.4 million) |
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Syndax Pharmaceuticals develops oncology therapies, including SNDX-5613 for acute myeloid leukemia and axatilimab for chronic graft versus big disease, with further pipeline assets specified arsenic Entinostat.
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The steadfast operates a clinical-stage biopharmaceutical model, generating gross chiefly done probe collaborations, licensing agreements, and milestone payments.
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It targets healthcare providers, probe institutions, and pharmaceutical partners focused connected innovative crab treatments and uncommon illness therapies.
Syndax Pharmaceuticals, Inc. is simply a clinical-stage biotechnology institution specializing successful the improvement of caller crab therapies. The institution leverages a focused pipeline strategy aimed astatine high-need oncology indications, supported by strategical collaborations and licensing agreements. Its accent connected targeted therapies and partnerships positions it to code unmet aesculapian needs successful hematologic malignancies and immune-related disorders.
It’s not astonishing that a money would marque a transaction similar this, cutting immoderate shares but holding onto a still-substantial stake. Syndax generated astir $172 cardinal successful full gross past year, driven by increasing uptake of its precocious launched therapies, including astir $124.8 cardinal from Revuforj and a meaningful publication from its Niktimvo collaboration. That benignant of commercialized traction is uncommon for companies astatine this stage, and it helps explicate wherefore the banal has surged much than 70% implicit the past year.
At the aforesaid time, the concern is inactive burning cash, with a full-year nett nonaccomplishment of astir $285 cardinal and elevated operating expenses tied to R&D and commercialization. That hostility betwixt maturation and profitability is precisely wherever progressive managers thin to rebalance alternatively than afloat exit.
Plus, wrong a portfolio heavy concentrated successful biotech names similar Cogent and Vera, this looks similar a measured accommodation alternatively than a displacement successful thesis. The presumption inactive accounts for much than 10% of assets, aft all, signaling continued conviction.

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