Jonathan Ponciano, The Motley Fool
Sun, February 22, 2026 astatine 11:57 AM CST 4 min read
Redmile Group disclosed a bargain of 1,316,390 shares of Scholar Rock Holding Corporation (NASDAQ:SRRK) successful a February 17, 2026, SEC filing, with the estimated transaction worth astatine $49.37 cardinal based connected quarterly mean pricing.
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Redmile Group’s bargain lifts its involvement successful Scholar Rock Holding Corporation to 16.94% of the fund’s 13F reportable assets nether management.
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Top holdings aft the filing:
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NASDAQ:SRRK: $229.98 cardinal (16.9% of AUM)
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NASDAQ:KRYS: $167.08 cardinal (12.3% of AUM)
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NASDAQ:NRIX: $153.54 cardinal (11.3% of AUM)
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NASDAQ:STOK: $128.04 cardinal (9.4% of AUM)
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NASDAQ:IMNM: $122.83 cardinal (9.0% of AUM)
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As of February 17, 2026, shares of Scholar Rock Holding Corporation were priced astatine $46.45, up 25.7% implicit the past twelvemonth and outperforming the S&P 500 by 13.39 percent points.
| Price (as of marketplace adjacent 2026-02-17) | $46.45 |
| Market Capitalization | $4.78 billion |
| Net Income (TTM) | $-353.43 million |
| One-Year Price Change | 25.71% |
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Scholar Rock Holding develops biopharmaceutical products targeting superior diseases, including Apitegromab for spinal muscular atrophy and SRK-181 for crab therapy resistance.
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The steadfast operates a research-driven exemplary focused connected discovering and advancing macromolecule maturation origin inhibitors, with gross imaginable from merchandise commercialization and strategical collaborations.
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It serves patients with neuromuscular disorders, cancer, and fibrotic diseases, targeting healthcare providers and biopharmaceutical partners.
Scholar Rock Holding Corporation is simply a clinical-stage biotechnology institution specializing successful the find and improvement of therapies that modulate macromolecule maturation origin signaling. The institution leverages a proprietary level to code unmet aesculapian needs successful neuromuscular, oncological, and fibrotic indications. Strategic collaborations and a focused pipeline presumption Scholar Rock to capitalize connected innovative subject successful high-impact therapeutic areas.
This acquisition signals a willingness to thin into that volatility alternatively than trim astir it. Scholar Rock enters 2026 with a wide catalyst path. According to an announcement past month, the institution plans a Biologics License Application resubmission for apitegromab successful spinal muscular atrophy and anticipates a imaginable U.S. motorboat pursuing support this year. It besides has astir $365 cardinal successful currency arsenic of December 31, with runway projected into 2027. That equilibrium expanse reduces near-term dilution risk, a cardinal information for semipermanent biotech investors.
Unlike diversified portfolios, this money concentrates heavy successful clinical-stage names. Scholar Rock present represents astir 17% of assets, alongside different high-conviction biotech positions. That attraction amplifies some upside and binary risk.
Shares are up astir 26% implicit the past year, modestly beating the broader marketplace and suggesting investors are already assigning worth to regulatory advancement and pipeline depth. Beyond apitegromab, programs successful FSHD and the SRK-439 myostatin inhibitor grow optionality.

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